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The  so-called ‘Diseases of Ageing’: Understanding Onset and Accumulation of Health Risks

Introduction:

As we journey through life, the ageing process inevitably brings about changes in our bodies, influencing our susceptibility to various health conditions. Referred to as the “diseases of ageing,” these ailments often emerge gradually, accumulating risks over time. In this evidence-based exploration, we will delve into the intricacies of diseases associated with ageing, including how and when these risks start to manifest and accumulate.

Understanding the Diseases of Aging

Cardiovascular Diseases

These Include heart disease and stroke and are prominent among the diseases of ageing. Research indicates that the risk of cardiovascular issues tends to rise after the age of 45, accelerating with each passing decade. Contributing factors such as high blood pressure, cholesterol levels and lifestyle choices play pivotal roles in the onset and progression of these conditions.

Neurodegenerative Disorders

Diseases like Alzheimer’s and Parkinson’s, characterized by cognitive decline and motor impairments, are often closely associated with ageing. The risks for neurodegenerative disorders start to climb around the age of 50, with genetic predisposition, environmental factors and lifestyle choices influencing the trajectory of these conditions.

Cancer

While cancer can affect individuals of any age, the risk significantly increases with ageing. Beyond the age of 50, the likelihood of developing cancer rises significantly. Lifestyle factors play a major role in the development and level of risks and increased vulnerability.

Osteoporosis

Bone health becomes a concern as we age, with osteoporosis being a prevalent condition. The risk of fractures and bone density loss becomes more pronounced post-menopause for women, and around the age of 70 for men. Dietary factors, hormonal change, and levels of physical inactivity contribute to the onset of osteoporosis.

Accumulation of Risks

The diseases of ageing are not isolated events but rather a culmination of various risk factors that accrue over time. Several key elements contribute to this accumulation, including:

Genetic Predisposition:

While genetics plays a role, it is not the sole determinant. Interactions between genetic predispositions and environmental factors can exacerbate or mitigate the risk of diseases of ageing.

Lifestyle Choices:

Unhealthy lifestyle habits, such as a sedentary routine, poor diet, smoking, and excessive alcohol consumption, significantly contribute to the acceleration of ageing-related diseases. These choices can amplify the impact of genetic and environmental factors.

Chronic Inflammation:

Persistent low-grade inflammation (or ‘inflammageing’, as it is now often termed), is often associated with ageing and contributes to the development and progression of various diseases. Lifestyle interventions, including a balanced diet and regular exercise, can help mitigate chronic inflammation.

Conclusion

In understanding the diseases of ageing, it becomes clear that the risks are not predetermined but are significantly influenced by a combination of genetic, environmental and lifestyle factors. The cumulative effect of these elements underscores the importance of proactive longevity wellness lifestyle actions.

The 4 Longer Life, Slow Down Ageing programme is a vital tool in achieving Longevity Wellness.

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